SIRC-CVS CYTOTOXICITY TEST: AN ALTERNATIVE FOR PREDICTING RODENT ACUTE SYSTEMIC TOXICITY
نویسندگان
چکیده
منابع مشابه
Sirc-cvs cytotoxicity test: an alternative for predicting rodent acute systemic toxicity.
An in vitro crystal violet staining method using the rabbit cornea-derived cell line (SIRC-CVS) has been developed as an alternative to predict acute systemic toxicity in rodents. Seventy-nine chemicals, the in vitro cytotoxicity of which was already reported by the Multicenter Evaluation of In vitro Toxicity (MEIC) and ICCVAM/ECVAM, were selected as test compounds. The cells were incubated wit...
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ژورنال
عنوان ژورنال: The Journal of Toxicological Sciences
سال: 2006
ISSN: 0388-1350,1880-3989
DOI: 10.2131/jts.31.371